Prof. Dr. Derya Ufuk Altıntaş

CURRICULUM VITAE

1-PERSONAL PROFILE

Name: Derya Ufuk                           Sex: Female

Surname: AltıntaşAdress:Çukurova University Medical Faculty,

                                                                        Dep of Pediatric Immunology and Allergy

Date of Birth:     1962E-mail: deryaufuk@gmail.com

2-EDUCATION and WORK EXPERIENCE

Medical School:Hacettepe University Medical Faculty (1979-1982)

Çukurova University Medical Faculty (1983-1985)

Fellowship: Çukurova University (1993-1995)

Asistant Professor: Çukurova University (1991-1995)

Associate Professor:Çukurova University (1996-2003)

Professor: Çukurova University (2003-)

3- PRESENT POSITION:

Professor of Medicine,  Cukurova University,  Medical School

4-PRIZES and AWARDS

5-JOURNAL PUBLICATIONS

a)Publications  Indexed  ByWeb  of  Science

1- Doğruel D, Bingöl G, Altıntaş DU, Yılmaz M, Kendirli SG. Prevalence of and risk factors for atopic dermatitis: A birth cohort study of infants in southeast Turkey.Allergol Immunopathol (Madr). 2016 May-Jun;44(3):214-20. 

2- Doğruel D, Bingöl G, Yılmaz M, Altıntaş DU. The ADAPAR Birth Cohort Study: Food Allergy Results at Five Years and New Insights.Int Arch Allergy Immunol. 2016;169(1):57-61. 

3- Doğruel D, Bingöl G, Altıntaş DU, Yılmaz M, Güneşer Kendirli S. Clinical Features of Food Allergy during the 1st Year of Life: The ADAPAR Birth Cohort Study.Int Arch Allergy Immunol. 2016;169(3):171-80. 

4- Inci D, Guggenheim R, Altintas DU, Wildhaber JH, Moeller A. Reported Exercise-Related Respiratory Symptoms and Exercise-Induced Bronchoconstriction in Asthmatic Children.J Clin Med Res. 2017 May;9(5):410-415.

5- Kisla Ekinci RM, Balci S, Bisgin A, Altintas DU, Yilmaz M. A homozygote TREX1 mutation in two siblings with different phenotypes: Chilblains and cerebral vasculitis.Eur J Med Genet. 2017 Dec;60(12):690-694.

6- Doğruel D, Yılmaz M, Bingöl G, Altıntaş DU, Güneşer Kendirli S. Fraction of exhaled nitric oxide as a predictor in juvenile idiopathic arthritis progression.Clin Rheumatol. 2017 Mar;36(3):541-546. 

7- Agin M, Tumgor G, Kont A, Karakoc GB, Altintas DU, Yilmaz M. Endoscopic findings in patients with familial Mediterranean fever and dyspeptic symptoms.Prz Gastroenterol. 2018;13(3):234-241.

8- Doğruel D, Bingöl G, Altıntaş DU, Seydaoğlu G, Erkan A, Yılmaz M. The Trend of Change of Allergic Diseases over the Years: Three Repeated Surveys from 1994 to 2014.Int Arch Allergy Immunol. 2017;173(3):178-182.

9- Sasihuseyinoglu AS, Yilmaz M, Altintaş DU, Dogruel D, Serbes M, Uğuz AH, Kiroğlu M.  Squamous Cell Carcinoma With Hyper-IgE Syndrome: A Case Report.J Pediatr Hematol Oncol. 2017 Sep 8. doi: 10.1097/MPH.0000000000000954.

10- Ekinci RMK, Balci S, Serbes M, Dogruel D, Altintas DU, Yilmaz M. Decreased serum vitamin B12 and vitamin D levels affect sleep quality in children with familial Mediterranean fever. Rheumatol Int. 2017 Nov 15. doi: 10.1007/s00296-017-3883-2.

11- Kisla Ekinci RM, Balci S, Bisgin A, Hershfield M, Atmis B, Dogruel D, Yilmaz M. Renal Amyloidosis in Deficiency of Adenosine Deaminase 2: Successful Experience With Canakinumab. Pediatrics. 2018 Nov;142(5). pii: e20180948. doi: 10.1542/peds.2018-0948.

12- Doğruel D, Bulut FD, Yılmaz M, Önenli-Mungan N, Altıntaş DU. Coexistence of 2 rare autosomal recessively inherited disorders manifesting with immune deficiency; IL-12 receptor β1 and biotinidase deficiencies. Turk J Pediatr. 2018;60(5):584-587. 

13- Miray Kisla Ekinci R, Balci S, Serbes M, Duyuler Ayçin G, Dogruel D, Ufuk Altintas D, Yilmaz M. Recurrent Henoch Schönlein purpura without renal involvement successfully treated with methotrexate.Scott Med J. 2019 May;64(2):74-77. 

14- Doğruel D, Serbes M, Şaşihüseyinoğlu AŞ, Yılmaz M, Altıntaş DU, Bişgin A. Clinical and genetic profiles of patients with X-linked agammaglobulinemia from southeast Turkey: Novel mutations in BTK gene.Allergol Immunopathol (Madr). 2019 Jan - Feb;47(1):24-31.

15- Ekinci RMK, Balci S, Bisgin A, Atmis B, Dogruel D, Altintas DU, Yilmaz M. MEFV gene variants in children with Henoch-Schönlein Purpura and association with clinical manifestations: a single center Mediterranean experience.Postgrad Med. 2019 Jan;131(1):68-72. 

16- Sasihuseyinoglu AS, Altıntaş DU, Soyupak S, Dogruel D, Yılmaz M, Serbes M, Duyuler G. Evaluation of high resolution computed tomography findings of cystic fibrosis.Korean J Intern Med. 2019 Mar;34(2):335-343. 

17- Kisla Ekinci RM, Balcı S, Mart OO, Tumgor G, Yavuz S, Celik H, Dogruel D, Altintas DU, Yilmaz M. Is Henoch-Schönlein purpura a susceptibility factor for functional gastrointestinal disorders in children?Rheumatol Int. 2019 Feb;39(2):317-322.

18- Balci S, Ekinci RMK, Bayazit AK, Melek E, Dogruel D, Altintas DU, Yilmaz M. Juvenile systemic lupus erythematosus: a single-center experience from southern Turkey.Clin Rheumatol. 2019 May;38(5):1459-1468. 

19- Ekinci RMK, Balcı S, Akay E, Tumgor G, Dogruel D, Altintas DU, Yilmaz M.Frequency of functional gastrointestinal disorders in children with familial Mediterranean fever. Clin Rheumatol. 2019 Mar;38(3):921-926.

20- Miray Kisla Ekinci R, Balcı S, Bisgin A, Tumgor G, Dogruel D, Yilmaz M.Hyperimmunoglobulinemia D syndrome with recurrent perianal abscess successfully treated with canakinumab. Scott Med J. 2019 Mar 12:36933019836405. doi: 10.1177/0036933019836405.

21- Ekinci RMK, Balci S, Sari Gokay S, Yilmaz HL, Dogruel D, Altintas DU, Yilmaz M. Do practical laboratory indices predict the outcomes of children with Henoch-Schönlein purpura?Postgrad Med. 2019 May;131(4):295-298.

 

 

b) Publications  Indexed  By  other  thanWeb of Science

c)National Publications

1-Özhan AK, Doğruel D, Altıntaş DU, Yılmaz M. Erken tip ilaç reaksiyonlarında beş yıllık Çukurova Üniversitesi Çocuk Alerji Kliniği deneyimi. Ege Journal of Medicine 2018;57(3):136-141

2- Doğruel D, Altıntaş DU, Yılmaz M. Astımlı çocuklarda fiziksel egzersizin klinik ve fonksiyonel parametrelere etkisi. Cukurova Med J 2018;43(2):457-462

3- Şaşihüseyinoğlu AŞ, Özhan AK, Serbes M, Duyuler GA, Bingöl G, Yılmaz M, Altıntaş DU. Distribution of Allergen Sensitization in Childhood with the Skin Test. Asthma Allergy Immunol 2017;15:43-48.

6-PRESENTATIONS:

a)Oral Presentations on National Meetings

1- Çocuklarda Besin Allerjisinin Karakteristik Özellikleri: Ulusal Çok Merkezli Çalışma. Ayşen Bingöl, Dilara Fatma Kocacık Uygun, Meltem Akdemir, Hakan Erengin, Dilek Doğruel, İlknur Bostancı, Ayşegül Ertuğrul, Suna Asilsoy, Seda Şirin Köse, Dost Zeyrek, Semanur Kuyucu, Tuğba Arıkoğlu, Zeynep Tamay, Sevgi Sipahi, Nihat Sapan, Şükrü Çekiç, Fazıl Orhan, Ebru Arık Yılmaz, Demet Can, Gülce Baranlı, Ceren Can, Betül Büyüktiryaki, Bülent Şekerel, Derya Ufuk Altıntaş. 25. Ulusal Alerj ve Klinik İmmünoloji Kongresi, Antalya, 17-21 Kasım 2018.

2- Selektif IgA eksikliği bulunan hastaların klinik fenotiplerinin araştırılması: Tek merkez deneyimi. Mahir Serbes, Dilek Doğruel, Şenay Şasihüseyinoğulları, Mustafa Yılmaz, Derya Ufuk Altıntaş25. Ulusal Alerji ve Klinik İmmünoloji Kongresi, Antalya, 17-21 Kasım 2018.

3- Çocuk alerji ve immünoloji polikliniğinde atopik dermatit tanısı konan çocuk hastaların klinik ve immünolojik profili. Ökkeş Özgür Mart, Mahir Serbes, Ayşe Şenay Şaşihüseyinoğlu, Dilek Doğruel, Derya Ufuk Altıntaş, Mustafa Yılmaz. 13. Uluslarası Katılımlı Çocuk Alerji ve Astım Kongresi, 20-23 Nisan 2018, Fethiye

4- Okul Öncesi Çocuklarda Astım Gelişimi İle İlişkili Risk Faktörlerinin Değerlendirilmesi. Ayşe Şenay Şaşihüseyinoğlu, Dilek Doğruel, Mahir Serbes, Derya Ufuk Altıntaş, Mustafa Yılmaz. 3. Çocuk Göğüs Hastalıkları Kongresi, İstanbul, 26-28 Eylül 2018

5- X’e Bağlı Agammaglobulinemi Hastaların Bruton Tirozin Kinaz Gen Mutasyon Sonuçları: Tek Merkez Deneyimi Mahir Serbes, Dilek Doğruel, Şenay Şasihüseyinoğulları, Mustafa Yılmaz, Derya Ufuk Altıntaş. 24. Ulusal Alerji ve Klinik İmmünoloji Kongresi, Antalya, 8-12 Kasım 2017.

6- Çukurova Üniversitesi Çocuk Alerji İmmünoloji Kliniği Subkutan Alerjen İmmünoterapisi Uygulaması:”Son 10 yıllık deneyim” Ayşe Şenay Şasi̇hüseyi̇noğlu, Derya Ufuk Altıntaş, Dilek Doğruel, Gülbin Bingöl, Cennet Çertmek, Mahir Serbes, Mustafa Yılmaz, Seval Güneşer Kendirli. 24. Ulusal Alerji ve Klinik İmmünoloji Kongresi, Antalya, 8-12 Kasım 2017

7- Çukurova Üniversitesi 2015-2016 Kistik Fibrosis Yenidoğan Taraması Sonuçları. Ayşe Şenay Şaşihüseyinoğlu, Derya Ufuk Altıntaş, Atıl Bişgin, Dilek Doğruel, Mustafa Yılmaz, Mahir Serbes, Ali Tanju Altunsu, Alper Acil. 2. Çocuk Göğüs Hastalıkları Kongresi, İstanbul, 27-29 Eylül 2017.

8- Altı-yedi yaş arası çocuklarda astım gelişimi ile ilişkili risk faktörlerinin değerlendirilmesi. Dilek Doğruel, Ayşe Şenay Şaşihüseyinoğlu, Mahir Serbes, Derya Ufuk Altıntaş, Mustafa Yılmaz. 12. Uluslarası Katılımlı Çocuk Alerji ve Astım Kongresi, Kuşadası, 23-26 Nisan 2017.

9- Adana bölgesinde ilköğretim çağı çocuklarında astım ve vizing prevalans çalışması. Doğruel D, Erkan A, Bingöl G, Altıntaş D,Yılmaz M, Şaşıhüseyinoğlu Ş. Çocuk Göğüs Hastalıkları 1. Kongresi, İstanbul, 29 Eylül-1 Ekim 2016,

10- İmmunoterapi Yapılan Hastalarda Premedikasyonun Yanetki Sıklığına Etkisi. Duyuler GA, AltıntaşDU, Serbes M, Şaşıhüseyinoğlu Ş, Yılmaz M, Doğruel D. 11. Ulusal Çocuk Alerji ve Astım Kongresi, Marmaris, 24-27 Nisan 2016

11- Adana Pediatrik Allerji (ADAPAR) Doğum Kohort Çalışmasında Besin Alerjisi Beş Yaş Verileri. Doğruel D, Altıntaş DU, Bingöl G, Yılmaz M. 11. Ulusal Çocuk Allerji ve Astım  Kongresi, Antalya, 28 Kasım-02 Aralık 2015

b)Poster Presentations on International Meetings

1- Genotype-Phenotype Correlation of Patients with Familial Mediterranean Fever in Childhood: Experience of a Single Center. Dilek Doğruel, Rabia Miray Kışla Ekinci, Sibel Balcı, Mustafa Yılmaz, Derya Ufuk Altıntaş. 9. International Congress of Familial Mediterranean Fever and Systemic Auto-Inflammatory Diseases, Kıbrıs, 5-7 Mayıs 2017.

2- Evaluation of high-resolution computed tomography findings of children with cystic fibrosis. Ayşe Şenay Şaşihüseyinoğlu, Derya Ufuk Altıntaş, Süreyya Soyupak, Dilek Doğruel, Mustafa Yılmaz. 2. Middle East Cystic Fibrosis Conference, İzmir, 22-24 Mart 2018.

3- Mahir Serbes, Dilek Doğruel, Ayşe Şenay Şaşihüseyinoğlu, Mustafa Yılmaz, Derya Ufuk Altıntaş. The clinical and immunologic features of patients with Immunoglobulin A deficiency: A tertiary center experience from Turkey. European Academy of Allergy and Clinical Immunology Congress 26-30 May 2018 Munich Germany.

4- Clinical and genetic profiles of patients with X linked agammaglobulinemia from southeast Turkey. Dilek Doğruel, Mahir Serbes, Mustafa Yılmaz, Derya Ufuk Altıntaş, Atıl Bişgin. European Academy of Allergy and Clinical Immunology Congress 26-30 May 2018 Munich Germany.

5- Clinical and genetic profiles of patients with X linked agammaglobulinemia from southeast Turkey: Novel Mutations in BTK Gene. Dilek Doğruel, Mahir Serbes, Ayşe Şenay Şaşihüseyinoğlu, Mustafa Yılmaz, Derya Ufuk Altıntaş. 18th Biennial Meeting of The European Society for Immunodeficiencies (ESID 2018), held in Lisbon, Portugal between October 24- 27 2018

6- ANAKINRA AS A SALVAGE TREATMENT FOR A SEVERE REFRACTORY CHRONIC GRANULOMATOUS DISEASE. Mahir Serbes, Dilek Doğruel, Ayşe Şenay Şaşihüseyinoğlu, Mustafa Yılmaz, Derya Ufuk Altıntaş. 18th Biennial Meeting of The European Society for Immunodeficiencies (ESID 2018), held in Lisbon, Portugal between October 24- 27 2018

 

7-PROFESIONAL MEMBERSHIPS

-        Turkish National Allergy and Clinical Immunology Assosiation

8-SCIENTEFIC PROJECTS

a)International Scientefic Projects:

b)National Scientefic Projects Supported by International Organizations:

Phase 3 Clinical Trial EFC14153: A randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy and safety of dupilumab in children 6 to <12 years of age with uncontrolled persistent asthma

Phase 3 Clinical Trial LTS14424:One year study to evaluate the long-term safety and tolerability of dupilumab in pediatric patients with asthma who participated in a previous

dupilumab asthma clinical study

 Phase 2 Clinical Trial CQMF149G2202: A multicenter, randomized, double-blind, active-controlled, 2 week treatment, parallel-group study to assess the efficacy and safety of indacaterol acetate delivered via the Concept1 inhalation device in children greater or equal to 6 and less than 12 years of age with asthma

9-EDITORIAL ACTIVITIES

10-CITATIONS ON WEB of SCIENCE

Total:                                                                                               

2017                                                   12

2018                                                   10

2019                                                     5

Total                                                  27       

1.

The ADAPAR Birth Cohort Study: Food Allergy Results at Five Years and New Insights

By: Dogruel, DilekBingol, GulbinYilmaz, Mustafa; et al.

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY   Volume: 169   Issue:   Pages: 57-61   Published: 2016

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2.Prevalence of and risk factors for atopic dermatitis: A birth cohort study of infants in southeast Turkey

By: Dogruel, D.Bingol, G.Altintas, D. U.; et al.

ALLERGOLOGIA ET IMMUNOPATHOLOGIA   Volume: 44   Issue:   Pages: 214-220   Published: MAY-JUN 2016

 

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3.Clinical Features of Food Allergy during the 1st Year of Life: The ADAPAR Birth Cohort Study

By: Dogruel, DilekBingol, GulbinAltintas, Derya Ufuk; et al.

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY   Volume: 169   Issue:   Pages: 171-180   Published: JUN 2016

 

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6.The Trend of Change of Allergic Diseases over the Years: Three Repeated Surveys from 1994 to 2014

By: Dogruel, DilekBingol, GulbinAltintas, Derya Ufuk; et al.

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY   Volume: 173   Issue:   Pages: 178-182   Published: 2017

 

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7. Fraction of exhaled nitric oxide as a predictor in juvenile idiopathic arthritis progression

By: Dogruel, DilekYilmaz, MustafaBingol, Gulbin; et al.

CLINICAL RHEUMATOLOGY   Volume: 36   Issue:   Pages: 541-546   Published: MAR 2017

 

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8.Decreased serum vitamin B-12 and vitamin D levels affect sleep quality in children with familial Mediterranean fever

By: Ekinci, Rabia Miray KislaBalci, SibelSerbes, Mahir; et al.

RHEUMATOLOGY INTERNATIONAL   Volume: 38   Issue:   Pages: 83-87   Published: JAN 2018

 

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9.Renal Amyloidosis in Deficiency of Adenosine Deaminase 2: Successful Experience With Canakinumab

By: Ekinci, Rabia Miray KislaBalci, SibelBisgin, Atil; et al.

PEDIATRICS   Volume: 142   Issue:     Article Number: e20180948   Published: NOV 2018

 

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10.

Is Henoch-Schonlein purpura a susceptibility factor for functional gastrointestinal disorders in children?

By: Ekinci, Rabia Miray KislaBalci, SibelMart, Okkes Ozgur; et al.

RHEUMATOLOGY INTERNATIONAL   Volume: 39   Issue:   Pages: 317-322   Published: FEB 2019

 

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